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シグナル伝達経路 血管新生 アポトーシス オートファジー 細胞周期・チェックポイント クロマチン・エピジェネティック 細胞骨格シグナル
DNA損傷・DNA修復 内分泌・ホルモン GPCR/Gタンパク質 免疫・炎症 JAK・STATシグナル MAPK 膜輸送体・イオンチャネル
代謝 微生物学・ウィルス学 神経科学 NF-Κb 酸化還元 PI3K/Akt/mTORシグナル プロテアーゼ・プロテアソーム
幹細胞 チロシンキナーゼ・アダプター ユビキチン その他 PROTAC
生物活性化合物ライブラリー ゼネラルバイオウアクティヴライブラリー 承認/再開発 医薬品ライブラリー 疾患別 化合物ライブラリー 標的/経路別 化合物ライブラリー 特徴的な生物活性化合物ライブラリー
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Cytokines and Growth Factors •   Cytokines •   Growth Factors Receptor Proteins •   Fc Receptors •   Cytokines and Growth Factor Receptors
CD Proteins •   T Cell CD Proteins •   B Cell CD Proteins Immune Checkpoint Proteins •   Co-inhibitory Immune Checkpoint Proteins •   Co-stimulatory Immune Checkpoint Proteins
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Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

検索結果

Search Results for " Transforming growth factor beta "

ターゲット

TGF-beta/Smad

46

阻害剤

9

天然化合物

112

リコンビナントタンパク質

1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T1748 Kartogenin KGN TGF-beta/Smad
Kartogenin (KGN) is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.
T5197 BIBF0775 ALK , TGF-beta/Smad
BIBF0775 is a selective TGFβ type I receptor (Alk5) inhibitor (IC50: 34 nM).
T2123 LY2109761 Autophagy , TGF-beta/Smad
LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor with Ki of 38 nM and 300 nM, respectively; shown to negatively affect the phosphorylation of Smad2.
T4662 SJ000291942 TGF-beta/Smad
SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway.
T4975 SM 16 ALK , TGF-beta/Smad
SM 16 is a ALK5/ALK4 kinase inhibitor (Ki: 10/1.5 nM).
T2462 SB-505124 ALK , TGF-beta/Smad
SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5.
T1800 GW788388 GW 788388 ALK , TGF-beta/Smad
GW788388 is a potent and selective inhibitor of ALK5, also inhibits TGF-(beta) type II receptor and activin type II receptor activities.
T1763 SB 525334 SB525334 ALK , TGF-beta/Smad
SB-525334 is a potent and selective inhibitor of the TGF-β1R and ALK5 (IC50: 14.3 nM).
T16708 R-268712 ALK , TGF-beta/Smad
R-268712 is a specific activin receptor-like kinase 5 (ALK5) inhibitor(IC50 of 2.5 nM). It is also an orally active transforming growth factor-β type I receptor inhibitor.
T1914 K02288 K 02288 ALK , TGF-beta/Smad
K 02288 is a novel small molecule inhibitor of ALK1/2/3/6.
T1942 DMH-1 DMH1 ALK , Autophagy , TGF-beta/Smad
DMH-1 is a potent and selective BMP inhibitor.
T4283 SRI-011381 TGF-beta/Smad
SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
T2510 Galunisertib LY2157299 TGF-beta/Smad
Galunisertib (LY2157299) is an orally available inhibitor of TGFβRI kinase (IC50: 56 nM) with potential antineoplastic activity.
T1943 ML347 LDN 193719 ALK , TGF-beta/Smad
ML347 (LDN 193719)(DN193719) is a highly specific ALK1/2 inhibitor ( IC50: 46/32 nM), and the selectivity for ALK2 is >300-fold than ALK3.
T23127 PD-161570 PD 161570 EGFR , FGFR , PDGFR , Src
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a...
T1449 Hydrochlorothiazide HCTZ Potassium Channel , Carbonic Anhydrase , TGF-beta/Smad
Hydrochlorothiazide (HCTZ) is a Thiazide Diuretic. The physiologic effect of hydrochlorothiazide is by means of Increased Diuresis.
T2098 A 77-01 A77-01 ALK , TGF-beta/Smad
A 77-01 is a potent inhibitor of TGF-(beta) type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.
T2109 SD-208 ALK5 Inhibitor V,SD208 TGF-beta/Smad
SD-208 (ALK5 Inhibitor V), a selective TGF-βRI (ALK5) inhibitor (IC50: 48 nM), is >100-fold selectivity over TGF-βRII.
T8730 BMS986260 TGF-beta/Smad
BMS-986260 is a selective, and orally bioavailable TGFβR1 inhibitor(IC50 = 1.6 nM).
T5125 LY3200882 TGF-beta/Smad
LY3200882 is a highly selective inhibitor of TGF-β receptor type 1 (TGFβRI).
T3031 A 83-01 ALK5 Inhibitor IV,A8301 ALK , TGF-beta/Smad
A 83-01 (ALK5 Inhibitor IV) is an inhibitor of the TGF-β type I receptors ALK5, ALK4, and ALK7 (IC50=12/45/7.5 nM). A 83-01 promotes the reprogramming of mouse fibroblasts into iPSCs. A 83-01 can be used in organoid cult...
T2048 LY-364947 LY 364947,HTS466284 MLK , Casein Kinase , TGF-beta/Smad , RIP kinase
LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGFβR-I.
T3636 (E)-SIS3 SIS3,SIS3 HCl TGF-beta/Smad
(E)-SIS3 (SIS3), a selective Smad3 inhibitor, can attenuate TGF-β1-dependent Smad3 phosphorylation and DNA binding. It has no effect on p38 MAPK, Smad2, ERK or PI3K signaling. It also inhibits TGF-β1-induced myofibroblas...
T1935 LDN193189 LDN-193189,DM-3189,LDN 193189 ALK , TGF-beta/Smad
LDN193189 (LDN-193189) (DM 3189) is a selective BMP signaling inhibitor, inhibiting the transcriptional activity of ALK2 and ALK3 (IC50s: 0.8/0.8/5.3/16.7 nM for ALK1/2/3/6).
T8330 BIO-013077-01 TGF-beta/Smad
BIO-013077-01 is a potent TGFbeta family type I receptors antagonist.
T1977 Dorsomorphin Compound C,BML-275 AMPK , Autophagy , TGF-beta/Smad
Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin induces autophagy, and possesses antitumor ...
T2386 Pirfenidone S-7701,AMR-69,S-7701,AMR69 CCR , TGF-beta/Smad
Pirfenidone (AMR69) is an inhibitor for TGF-β production and TGF-β stimulated collagen production. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors, thereby slowing tum...
T1944 LDN-214117 ALK , TGF-beta/Smad
LDN-214117 is a potent and selective ALK2 inhibitor.
T2273 ITD-1 TGF-beta/Smad
ITD-1 is a potent and highly selective TGFβ pathway inhibitor.
T7799 BMP signaling agonist sb4 SB 4 TGF-beta/Smad
BMP signaling agonist sb4 (SB 4) is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)
T6496 Vactosertib TEW-7197,EW-7197 ALK , TGF-beta/Smad
Vactosertib (EW-7197) is an orally bioavailable inhibitor of the serine/threonine kinase, transforming growth factor (TGF)-beta receptor type 1 (TGFBR1), also known as activin receptor-like kinase 5 (ALK5), with potentia...
T5129 SRI-011381 hydrochloride SRI-011381 hydrochloride [1629138-41-5(free base)] TGF-beta/Smad
SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
T6337 RepSox ALK5 Inhibitor II,SJN 2511,E-616452 ALK , TGF-beta/Smad
RepSox (ALK5 Inhibitor II) is a TGFβR-1/ALK5 inhibitor that selectively inhibits the binding of ATP to ALK5 and the autophosphorylation of ALK5 (IC50=23/4 nM). RepSox induces adipogenesis in MEFs cells.
T1900 LDN-212854 LDN212854,BMP Inhibitor III ALK , TGF-beta/Smad
LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors; possesses differences towards ALK2(IC50=1.3 nM) versus ALK1/3 compared to other inhibitors.
T9010 IMM-H007 Others , AMPK
IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression
T1726 SB-431542 SB 431542 ALK , TGF-beta/Smad
SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective. SB 431542 also has inhibitory activity against ALK4 and ALK7 but not other proteins. SB 431542 can be used for induced differentiatio...
T6146 Dorsomorphin dihydrochloride BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride AMPK , Autophagy , TGF-beta/Smad
Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases.
T11052L Disitertide acetate P144 acetate,Disitertide acetate(272105-42-7 Free base) TGF-beta/Smad
Disitertide acetate (P144 acetate) is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide acetate is also a PI3K inhibitor and an ...
T69212 LY-580276
LY-580276 is an inhibitor of the type I transforming growth factor beta receptor (TβRI).
T25700 Levormeloxifene
Levormeloxifene is a selective modulator of the estrogen receptor. It inhibits the production of vaginal tropoelastin and transforming growth factor-beta 1.
T80272 Vicatertide SB-01
Vicatertide is an inhibitor of transforming growth factor beta-1 (TGF-β1) [1].
T79543 J27644 HDAC
J27644 is a potent HDAC (histone deacetylase) inhibitor that mitigates TGF-β (transforming growth factor beta)-induced pulmonary fibrosis [1].
T75717 Disitertide diammonium
Disitertide (P144) diammonium, a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor, is specifically engineered to prevent its receptor interaction. Additionally, it serves as a PI3K inhibitor and induces apop...
T75716 Disitertide TFA
Disitertide (P144) TFA is a peptide-based inhibitor of transforming growth factor-beta 1 (TGF-β1), specifically engineered to prevent its interaction with the receptor. Additionally, it functions as a PI3K inhibitor and ...
T79603 3,7-DMF TGF-beta/Smad
3,7-Dimethylfumarate (3,7-DMF) serves as an oral inhibitor of transforming growth factor-beta 1 (TGF-β1)-mediated hepatic stellate cell (HSC) activation. By inducing antioxidant gene expression and scavenging reactive ox...
T35438 (5E)-7-Oxozeaenol
(5E)-7-Oxozeaenol is a resorcylic acid lactone that has been found in the fungus MSX 63935 and has enzyme inhibitory and anticancer activities.1,2 It inhibits TGF-β-activated kinase 1 (TAK-1; IC50 = 1.3 μM).1 (5E)-7-Oxoz...

Compounds

Kartogenin
T1748
Synonym: KGN
Target: TGF-beta/Smad
BIBF0775
T5197
Synonym:
Target: ALK, TGF-beta/Smad
LY2109761
T2123
Synonym:
Target: Autophagy, TGF-beta/Smad
SJ000291942
T4662
Synonym:
Target: TGF-beta/Smad
SM 16
T4975
Synonym:
Target: ALK, TGF-beta/Smad
SB-505124
T2462
Synonym:
Target: ALK, TGF-beta/Smad
GW788388
T1800
Synonym: GW 788388
Target: ALK, TGF-beta/Smad
SB 525334
T1763
Synonym: SB525334
Target: ALK, TGF-beta/Smad
R-268712
T16708
Synonym:
Target: ALK, TGF-beta/Smad
K02288
T1914
Synonym: K 02288
Target: ALK, TGF-beta/Smad
DMH-1
T1942
Synonym: DMH1
Target: ALK, Autophagy, TGF-beta/Smad
SRI-011381
T4283
Synonym:
Target: TGF-beta/Smad
Galunisertib
T2510
Synonym: LY2157299
Target: TGF-beta/Smad
ML347
T1943
Synonym: LDN 193719
Target: ALK, TGF-beta/Smad
PD-161570
T23127
Synonym: PD 161570
Target: EGFR, FGFR, PDGFR, Src
Hydrochlorothiazide
T1449
Synonym: HCTZ
Target: Potassium Channel, Carbonic Anhydrase, TGF-beta/Smad
A 77-01
T2098
Synonym: A77-01
Target: ALK, TGF-beta/Smad
SD-208
T2109
Synonym: ALK5 Inhibitor V,SD208
Target: TGF-beta/Smad
BMS986260
T8730
Synonym:
Target: TGF-beta/Smad
LY3200882
T5125
Synonym:
Target: TGF-beta/Smad
A 83-01
T3031
Synonym: ALK5 Inhibitor IV,A8301
Target: ALK, TGF-beta/Smad
LY-364947
T2048
Synonym: LY 364947,HTS466284
Target: MLK, Casein Kinase, TGF-beta/Smad, RIP kinase
(E)-SIS3
T3636
Synonym: SIS3,SIS3 HCl
Target: TGF-beta/Smad
LDN193189
T1935
Synonym: LDN-193189,DM-3189,LDN 193189
Target: ALK, TGF-beta/Smad
BIO-013077-01
T8330
Synonym:
Target: TGF-beta/Smad
Dorsomorphin
T1977
Synonym: Compound C,BML-275
Target: AMPK, Autophagy, TGF-beta/Smad
Pirfenidone
T2386
Synonym: S-7701,AMR-69,S-7701,AMR69
Target: CCR, TGF-beta/Smad
LDN-214117
T1944
Synonym:
Target: ALK, TGF-beta/Smad
ITD-1
T2273
Synonym:
Target: TGF-beta/Smad
BMP signaling agonist sb4
T7799
Synonym: SB 4
Target: TGF-beta/Smad
Vactosertib
T6496
Synonym: TEW-7197,EW-7197
Target: ALK, TGF-beta/Smad
SRI-011381 hydrochloride
T5129
Synonym: SRI-011381 hydrochloride [1629138-41-5(free base)]
Target: TGF-beta/Smad
RepSox
T6337
Synonym: ALK5 Inhibitor II,SJN 2511,E-616452
Target: ALK, TGF-beta/Smad
LDN-212854
T1900
Synonym: LDN212854,BMP Inhibitor III
Target: ALK, TGF-beta/Smad
IMM-H007
T9010
Synonym:
Target: Others, AMPK
SB-431542
T1726
Synonym: SB 431542
Target: ALK, TGF-beta/Smad
Dorsomorphin dihydrochloride
T6146
Synonym: BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride
Target: AMPK, Autophagy, TGF-beta/Smad
Disitertide acetate
T11052L
Synonym: P144 acetate,Disitertide acetate(272105-42-7 Free base)
Target: TGF-beta/Smad
LY-580276
T69212
Synonym:
Target:
Levormeloxifene
T25700
Synonym:
Target:
Vicatertide
T80272
Synonym: SB-01
Target:
J27644
T79543
Synonym:
Target: HDAC
Disitertide diammonium
T75717
Synonym:
Target:
Disitertide TFA
T75716
Synonym:
Target:
3,7-DMF
T79603
Synonym:
Target: TGF-beta/Smad
(5E)-7-Oxozeaenol
T35438
Synonym:
Target:
カタログ番号 製品名 別名 ターゲット
TQ0184 Chebulinic acid ATPase , Proton pump , DNA/RNA Synthesis , Antibacterial , TGF-beta/Smad
Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.
TN2081 Maohuoside A MAPK
Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways.
T2754 Oxymatrine Oxysophoridine,Matrine N-oxide Influenza Virus , Autophagy , TGF-beta/Smad
Oxymatrine (Oxysophoridine) is an alkaloid isolated from Sophora flavescens, used as the antibiotic. It is a traditional Chinese medicine used in the treatment against hepatitis B virus.It can also inhibit iNOS expressio...
T13741 Isoviolanthin Others
Isoviolanthin reduces the migratory and invasive capacities of TGF-β1-treated HCC cells without cytotoxic effects on normal live cells and has potential as a therapeutic agent for the treatment of advanced-stage metastat...
T2896 Alantolactone helenin,Eupatal,Helenine,(+)-Alantolactone,Alant camphor,Inula camphor Apoptosis , STAT , TGF-beta/Smad
Alantolactone (Inula camphor)(Alant camphor), a sesquiterpene lactone, has potential activity against triple-negative breast Y MDA-MB-231 cells by suppressing the signal transducer and activator of transcription 3 (STAT3...
T3025 Asiaticoside BRN0078195,CCRIS8995,Emdecassol,Ba 2742,Madecassol,NSC166062 Apoptosis , p38 MAPK , Reactive Oxygen Species , Endogenous Metabolite , TGF-beta/Smad
Asiaticoside (Emdecassol) (Madecassol) is the active chemical component of the plant Centella asiatica. Asiaticoside is used to study potential treatments for wounds and burns.
T6856 Halofuginone Tempostatin,empostatin,RU-19110 Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal.
T5247 Trimethylamine N-oxide dihydrate TMANO Dihydrate Others , Endogenous Metabolite
Trimethylamine N-oxide dihydrate (TMANO Dihydrate), a product of the oxidation of trimethylamine, is considered as a protein stabilizer that may serve to counteract urea, the major osmolyte of sharks, skates and rays.
T3524 Halofuginone hydrobromide Tempostatin,RU-19110 (hydrobromide),Stenorol Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce...

天然物製品

Chebulinic acid
TQ0184
Synonym:
Target: ATPase, Proton pump, DNA/RNA Synthesis, Antibacterial, TGF-beta/Smad
Maohuoside A
TN2081
Synonym:
Target: MAPK
Oxymatrine
T2754
Synonym: Oxysophoridine,Matrine N-oxide
Target: Influenza Virus, Autophagy, TGF-beta/Smad
Isoviolanthin
T13741
Synonym:
Target: Others
Alantolactone
T2896
Synonym: helenin,Eupatal,Helenine,(+)-Alantolactone,Alant camphor,Inula camphor
Target: Apoptosis, STAT, TGF-beta/Smad
Asiaticoside
T3025
Synonym: BRN0078195,CCRIS8995,Emdecassol,Ba 2742,Madecassol,NSC166062
Target: Apoptosis, p38 MAPK, Reactive Oxygen Species, Endogenous Metabolite, TGF-beta/Smad
Halofuginone
T6856
Synonym: Tempostatin,empostatin,RU-19110
Target: Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
Trimethylamine N-oxide dihydrate
T5247
Synonym: TMANO Dihydrate
Target: Others, Endogenous Metabolite
Halofuginone hydrobromide
T3524
Synonym: Tempostatin,RU-19110 (hydrobromide),Stenorol
Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad

Recombinant Proteins

Species：
Human (64)
Mouse (19)
Canine (5)
Cynomolgus (5)
Rat (4)
Mouse,Rat (3)
Bovine (2)
Cynomolgus,Rhesus (2)
Rhesus (2)
Chicken (1)
Expression System：
HEK293 (66)
Human Cells (22)
E. coli (16)
Baculovirus (3)
Baculovirus-Insect Cells (3)
CHO (2)
Tag：
His (38)
hFc (18)
His,hFc (6)
N-terminal 10xHis-tagged and C-terminal Myc-tagged (6)
None (5)
C-mFc-Avi (4)
C-6His (3)
N-8His-Avi (3)
N-Avi (3)
N-terminal 6xHis-SUMO-tagged (3)
カタログ番号 製品名 Species Expression System
TMPY-02638 TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant Human,Rhesus,Cynomolgus,Canine CHO
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-03945 Latent TGF beta 1 Protein, Rat, Recombinant (His) Rat HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-04211 Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-00608 TGF beta 1 Protein, Rat/Mouse, Recombinant Mouse,Rat HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-00500 Latent TGF beta 1 Protein, Mouse, Recombinant (His) Mouse HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPJ-00254 TGF beta 3 Protein, Human/Mouse/Rat, Recombinant Human,Mouse,Rat Human Cells
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes acti...
TMPY-01133 Latent TGF beta 1 Protein, Human, Recombinant (His) Human HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-06247 TGF beta 3 Protein, Human, Recombinant (hFc) Human HEK293
TGF beta 3 Protein, Human, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 41.2 kDa. Accession number: P10600-1
TMPJ-00249 TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated Human Human Cells
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-...
TMPY-00413 TGF beta 2 Protein, Mouse, Recombinant (His) Mouse HEK293
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a...
TMPJ-00258 TGF beta 2 Protein, Human, Recombinant Human Human Cells
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. T...
TMPJ-00261 TGF beta 2 Protein, Mouse/Rat, Recombinant Mouse,Rat Human Cells
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofaci...
TMPY-01009 TGFBI Protein, Human, Recombinant (His) Human HEK293
TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several ...
TMPY-05157 TGFBR2 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPJ-00335 TGFBR2 Protein, Mouse, Recombinant (His) Mouse Human Cells
Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinit...
TMPY-00229 Latent TGF beta 1 Protein, Canine, Recombinant (His) Canine HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-03171 TGFBR2 Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPY-03082 TGFBR2 Protein, Rat, Recombinant (hFc) Rat HEK293
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPY-03649 TGFBR3 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Betaglycan also known as transforming growth factor beta receptor III (TGFBR3), is a cell-surface chondroitin sulfate / heparan sulfate proteoglycan. TGFBR3 is a transforming growth factor (TGF)-beta type III receptor. T...
TMPY-04577 TGF beta 2 Protein, Rhesus, Recombinant (His) Rhesus HEK293
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a...
TMPY-00231 TGF beta 2 Protein, Canine, Recombinant (His) Canine HEK293
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a...
TMPY-02224 TGFBR3 Protein, Mouse, Recombinant (His) Mouse HEK293
Betaglycan also known as transforming growth factor beta receptor III (TGFBR3), is a cell-surface chondroitin sulfate / heparan sulfate proteoglycan. TGFBR3 is a transforming growth factor (TGF)-beta type III receptor. T...
TMPJ-00622 Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) Cynomolgus Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPY-05313 Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated Mouse HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPJ-00256 Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated Human Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPJ-00772 Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPY-05521 Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated Human HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPJ-00260 Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated Human Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPY-05314 TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated Mouse HEK293
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a...
TMPJ-00259 TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated Human Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPJ-00250 LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated Human Human Cells
Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activ...
TMPJ-00771 TGF beta 1 Protein, Mouse/Rat, Recombinant Mouse,Rat Human Cells
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differen...
TMPJ-00238 Lefty-A Protein, Human, Recombinant (His) Human Human Cells
Left-right determination factor 2(LEFTY2) is a secreted protein which belongs to the TGF-beta family. Lefty was first identified in a screen for undifferentiated cell-specific cDNAs from the P19 mouse embryonal carcinoma...
TMPY-05810 TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated Human HEK293
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPY-04366 ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST) Human Baculovirus-Insect Cells
Transforming growth factor, beta receptor I, also known as Transforming growth factor-beta receptor type I , Serine / threonine-protein kinase receptor R4, Activin receptor-like kinase 5, SKR4, ALK-5, and TGFBR1, is a si...
TMPY-05771 ALK-5 Protein, Human, Recombinant (hFc) Human HEK293
Transforming growth factor, beta receptor I, also known as Transforming growth factor-beta receptor type I , Serine / threonine-protein kinase receptor R4, Activin receptor-like kinase 5, SKR4, ALK-5, and TGFBR1, is a si...
TMPY-01358 ALK-5 Protein, Human, Recombinant (His & hFc) Human HEK293
Transforming growth factor, beta receptor I, also known as Transforming growth factor-beta receptor type I , Serine / threonine-protein kinase receptor R4, Activin receptor-like kinase 5, SKR4, ALK-5, and TGFBR1, is a si...
TMPY-05508 TGFBR2 Protein, Human, Recombinant (hFc) Human HEK293
TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein. TGFBR2 is comprised of a C-terminal protein kinase domain and an N-terminal ectodomain. The ectodoma...
TMPJ-00333 TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) Mouse Human Cells
Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinit...
TMPJ-00334 TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) Mouse Human Cells
Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinit...
TMPJ-01129 SMAD1 Protein, Human, Recombinant (GST) Human E. coli
SMAD Family Member 1 (SMAD1) is a member of the dwarfin/SMAD family. SMAD1 has the highest expression in the heart and skeletal muscle, containing one MAD homology 1 domain and one MAD homology 2 domain, As a transcripti...
TMPK-00305 TGFBR1 Protein, Human, Recombinant (mFc & Avi) Human HEK293
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup...
TMPY-01395 CTHRC1 Protein, Human, Recombinant (His) Human HEK293
Collagen triple helix repeat-containing protein 1, also known as Protein NMTC1, and CTHRC1, is a secreted protein that is glycosylated and highly conserved from lower chordates to mammals. CTHRC1 expression was not detec...
TMPY-01168 ALK-1 Protein, Human, Recombinant (His) Human HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-00835 IGFBP-3 Protein, Human, Recombinant (His) Human HEK293
The Insulin-like Growth Factor (IGF) signaling system plays a central role in cellular growth, differentiation, and proliferation. IGFBP3 is the most abundant IGF binding protein in human serum and is a growth inhibitory...
TMPY-04018 LRG1 Protein, Human, Recombinant Human HEK293
LRG1 (Leucine-Rich Alpha-2-Glycoprotein 1) is a Protein Coding gene. LRG1 belongs to the leucine-rich repeat (LRR) family. Members of this family are involved in protein-protein interaction, signal transduction, and cell...
TMPY-00664 ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc) Human HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-02474 ANGPT2/Angiopoietin-2 Protein, Mouse, Recombinant (His) Mouse HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-04168 ANGPT2/Angiopoietin-2 Protein, Cynomolgus, Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-01059 BMPR2 Protein, Human, Recombinant (His) Human HEK293
The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin...
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TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant
TMPY-02638
Species: Human,Rhesus,Cynomolgus,Canine
Expression System: CHO
Latent TGF beta 1 Protein, Rat, Recombinant (His)
TMPY-03945
Species: Rat
Expression System: HEK293
Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)
TMPY-04211
Species: Cynomolgus
Expression System: HEK293
TGF beta 1 Protein, Rat/Mouse, Recombinant
TMPY-00608
Species: Mouse,Rat
Expression System: HEK293
Latent TGF beta 1 Protein, Mouse, Recombinant (His)
TMPY-00500
Species: Mouse
Expression System: HEK293
TGF beta 3 Protein, Human/Mouse/Rat, Recombinant
TMPJ-00254
Species: Human,Mouse,Rat
Expression System: Human Cells
Latent TGF beta 1 Protein, Human, Recombinant (His)
TMPY-01133
Species: Human
Expression System: HEK293
TGF beta 3 Protein, Human, Recombinant (hFc)
TMPY-06247
Species: Human
Expression System: HEK293
TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated
TMPJ-00249
Species: Human
Expression System: Human Cells
TGF beta 2 Protein, Mouse, Recombinant (His)
TMPY-00413
Species: Mouse
Expression System: HEK293
TGF beta 2 Protein, Human, Recombinant
TMPJ-00258
Species: Human
Expression System: Human Cells
TGF beta 2 Protein, Mouse/Rat, Recombinant
TMPJ-00261
Species: Mouse,Rat
Expression System: Human Cells
TGFBI Protein, Human, Recombinant (His)
TMPY-01009
Species: Human
Expression System: HEK293
TGFBR2 Protein, Human, Recombinant (His)
TMPY-05157
Species: Human
Expression System: Baculovirus-Insect Cells
TGFBR2 Protein, Mouse, Recombinant (His)
TMPJ-00335
Species: Mouse
Expression System: Human Cells
Latent TGF beta 1 Protein, Canine, Recombinant (His)
TMPY-00229
Species: Canine
Expression System: HEK293
TGFBR2 Protein, Rhesus, Recombinant (hFc)
TMPY-03171
Species: Rhesus
Expression System: HEK293
TGFBR2 Protein, Rat, Recombinant (hFc)
TMPY-03082
Species: Rat
Expression System: HEK293
TGFBR3 Protein, Human, Recombinant (His)
TMPY-03649
Species: Human
Expression System: Baculovirus-Insect Cells
TGF beta 2 Protein, Rhesus, Recombinant (His)
TMPY-04577
Species: Rhesus
Expression System: HEK293
TGF beta 2 Protein, Canine, Recombinant (His)
TMPY-00231
Species: Canine
Expression System: HEK293
TGFBR3 Protein, Mouse, Recombinant (His)
TMPY-02224
Species: Mouse
Expression System: HEK293
Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His)
TMPJ-00622
Species: Cynomolgus
Expression System: Human Cells
Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated
TMPY-05313
Species: Mouse
Expression System: HEK293
Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00256
Species: Human
Expression System: Human Cells
Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPJ-00772
Species: Mouse
Expression System: Human Cells
Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated
TMPY-05521
Species: Human
Expression System: HEK293
Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00260
Species: Human
Expression System: Human Cells
TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated
TMPY-05314
Species: Mouse
Expression System: HEK293
TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated
TMPJ-00259
Species: Human
Expression System: Human Cells
LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00250
Species: Human
Expression System: Human Cells
TGF beta 1 Protein, Mouse/Rat, Recombinant
TMPJ-00771
Species: Mouse,Rat
Expression System: Human Cells
Lefty-A Protein, Human, Recombinant (His)
TMPJ-00238
Species: Human
Expression System: Human Cells
TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated
TMPY-05810
Species: Human
Expression System: HEK293
ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST)
TMPY-04366
Species: Human
Expression System: Baculovirus-Insect Cells
ALK-5 Protein, Human, Recombinant (hFc)
TMPY-05771
Species: Human
Expression System: HEK293
ALK-5 Protein, Human, Recombinant (His & hFc)
TMPY-01358
Species: Human
Expression System: HEK293
TGFBR2 Protein, Human, Recombinant (hFc)
TMPY-05508
Species: Human
Expression System: HEK293
TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)
TMPJ-00333
Species: Mouse
Expression System: Human Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)
TMPJ-00334
Species: Mouse
Expression System: Human Cells
SMAD1 Protein, Human, Recombinant (GST)
TMPJ-01129
Species: Human
Expression System: E. coli
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
TMPK-00305
Species: Human
Expression System: HEK293
CTHRC1 Protein, Human, Recombinant (His)
TMPY-01395
Species: Human
Expression System: HEK293
ALK-1 Protein, Human, Recombinant (His)
TMPY-01168
Species: Human
Expression System: HEK293
IGFBP-3 Protein, Human, Recombinant (His)
TMPY-00835
Species: Human
Expression System: HEK293
LRG1 Protein, Human, Recombinant
TMPY-04018
Species: Human
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)
TMPY-00664
Species: Human
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Mouse, Recombinant (His)
TMPY-02474
Species: Mouse
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-04168
Species: Cynomolgus,Rhesus
Expression System: HEK293
BMPR2 Protein, Human, Recombinant (His)
TMPY-01059
Species: Human
Expression System: HEK293
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カタログ番号 製品名
L4100 TGF-beta/Smad Compound Library

184 compounds
A unique collection of 184 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;

ライブラリー

TGF-beta/Smad Compound Library
L4100
Compounds: 184
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